Time # Teams Opener % SC odds Picks
Thursday, September 4th, 2025
8:20pm
451
452
Cowboys
Eagles
-7 -105
+46½ -110
0%
0%
47 -110
-7 -110
47 -110
-7 -105
47 -105
-6½ -115
46½ -115
-7 -110
47 -110
-7 -110
46½ -110
-7 -110
 
Friday, September 5th, 2025
8:00pm
453
454
Chiefs
Chargers
+44 -110
-2½ -110
0%
0%
-2½ -110
45 -110
-2½ -110
45 -115
-3 +100
45 -105
-2½ -110
44½ -115
-2½ -110
45 -110
-2½ -115
45½ -110
 
Sunday, September 7th, 2025
1:00pm
455
456
Steelers
Jets
+39½ -110
-3 -110
0%
0%
-3 +100
39½ -120
-3 +105
39½ -110
-3 +105
39½ -110
-3 +100
39½ -110
-3 +100
39 -110
-2½ -120
38½ -110
 
1:00pm
457
458
Dolphins
Colts
-1½ -110
+45½ -110
0%
0%
-1 -110
47 -110
-1 -110
47 -110
-1 -110
46 -110
-2 -105
46½ -110
-1½ -110
47 -110
-1 -110
47 -110
 
1:00pm
459
460
Panthers
Jaguars
-2½ -120
+46½ -110
0%
0%
46½ -105
-2½ -115
46½ -110
-2½ -120
46½ -110
-2½ -120
46½ -110
-2½ -115
46½ -110
-2½ -110
46 -110
-2½ -115
 
1:00pm
461
462
Giants
Commanders
-7 -110
+46 -110
0%
0%
46½ -110
-6½ -110
46½ -110
-6½ -110
46½ -110
-6½ -105
46 -110
-7 -111
46½ -110
-7 +100
46½ -110
-6½ -110
 
1:00pm
463
464
Bengals
Browns
+46 -110
-6 -115
0%
0%
-5½ -110
46 -110
-5½ -110
46 -110
-5½ -110
46 -110
-6 -110
46½ -110
-5½ -110
46½ -110
-5½ -110
46½ -110
 
1:00pm
465
466
Raiders
Patriots
-2½ -110
+43½ -110
0%
0%
42 -110
-3 -110
42 -110
-3 -103
42 -105
-3 -110
41½ -115
-2½ -120
42 -110
-3 -110
42½ -110
-3 -105
 
1:00pm
467
468
Cardinals
Saints
+42 -110
-3 -125
0%
0%
-6 -110
42½ -110
-6 -110
42½ -110
-5 -120
42½ -110
-6 -110
43 -110
-6 -110
42½ -110
-6 -110
42 -110
 
1:00pm
469
470
Bucs
Falcons
+48 -110
-2 -115
0%
0%
-2½ -110
49½ -110
-2½ -110
48½ -115
-2½ -115
49½ -110
-2½ -115
50 -110
-2½ -110
49½ -110
-2½ -115
49½ -110
(1)
4:05pm
471
472
Titans
Broncos
-7 -113
+42 -110
0%
0%
41½ -110
-7½ -110
41½ -110
-7½ -110
41½ +100
-7½ -115
41½ -110
-7½ +100
41½ -110
-7½ -110
41½ -110
-7½ -110
 
4:05pm
473
474
49ers
Seahawks
+45½ -110
-2½ -110
0%
0%
-1½ -110
45½ -110
-1½ -110
45½ -110
-1½ -110
45½ -110
-2 -110
46 -110
-1½ -110
46 -110
-1½ -110
46 -110
 
4:25pm
475
476
Lions
Packers
PK -110
PK -110
0%
0%
49½ -110
-1½ -110
49½ -110
-1½ -110
49½ -110
-1½ -105
50 -110
-1 -120
49½ -110
-1½ -110
48½ -110
-2½ -110
 
4:25pm
477
478
Texans
Rams
-3 -110
+46 -110
0%
0%
45½ -105
-2½ -115
46 -110
-2½ -115
45½ -110
-3 -110
45½ -110
-2½ -115
45½ -110
-3 +100
45½ -110
-2½ -120
 
8:20pm
479
480
Ravens
Bills
-1 -110
+53½ -110
0%
0%
52½ -105
-1 -115
52½ -105
-2 -115
52 -115
-1½ -110
52½ -108
-1 -115
52½ -110
-1½ -110
51½ -110
-1 -110
 
Monday, September 8th, 2025
8:15pm
481
482
Vikings
Bears
PK -110
PK -110
0%
0%
44 -110
-1 -110
44 -110
-1 -105
44 -105
-1 -110
44 -110
-1 -110
44 -110
PK -110
44 -110
PK -110