The Indianapolis Colts are facing some serious QB issues heading to Tennessee to take on the Titans. Last week QB Carson Wentz suffered an ankle injury, and then another, with the second sending him to the sidelines. Wentz is listed as questionable, and if he plays, he will likely be hampered. Their 2nd string QB Sam Ehlinger went down in preseason leaving Jacob Eason as perhaps the starter in this one. Eason did not look good in his backup role last week, going 2-5 with an INT. Regardless who starts, the Titan's are likely going to bring pressure. Tennessee has had a penchant for starting slow, and finishing fast. There will be a point in time, where that changes, as a lot of it is random, but when it keeps occurring it also becomes psychological. This week the Titans should have all the tools to win, and with a less than healthy Wentz, or a vastly inexperienced Eason, the Titans should be able to breakaway in this one. Make the play on Tennessee.

Laying a TD or more on the road in the NFL has always been a tough cover, especially for a team traveling across the country. A road favorite of more than -7 in the first 3 weeks of the season are just 14-26 ATS. Making the cross country trip makes this game against the body clock of the Cardinals. Jacksonville looks to have a weakened secondary because of injuries and signed Nevin Lawson this week. QB Trevor Lawrence is airing it out, but the results have been up and down thus far. Jacksonville should have success on the ground to help shorten the game. Kyler Murray has not had a lot of success playing as a favorite where the Cardinals are 4-10 ATS. Playing as a favorite off a game where they had a 2 turnover or more advantage in their last game is 97-53 ATS. Make the play on Jacksonville.

Seattle had a big halftime lead vs Tennessee last week, and let it slip away in the 2nd half in a 33-30 loss. The Titans went for over 500 yards on the Seahawks. Minnesota despite allowing a considerable amount of points has one of the top run defenses in the league, and they will be able to get pressure on Wilson. Cousin's has 6 starts vs Seattle and 5 of the games have played under, and the Minnesota defense has historically been much better at home, and this will be the home opener for the Vikings. Russell Wilson is 15-7 to the under when playing as a road favorite. I like the under in this one.

The Bears rookie QB Justin Fields has struggled and the Bears are generating just 4.2 passing yards per attempt to a schedule of teams that allow 5.7. He is holding the ball way too long, and Andy Dalton has been ruled out this week so it is all on Fields. I would expect the Bears somewhat above average running game be in play a lot more, along with the short quick passing game. The Bears will contain the Browns running game, and that will put the game in Baker Mayfield's hands but he will be without key target Jarvis Landry. Field's ran the ball 10 times last week and he should have some scrambling success in this one. The Brown's have not looked all that dominating this season, and getting a TD plus in the NFl is enticing, especially with a team that defends well. Mayfield is just 14-21 ATS when the total is 41.5 to 48.5 and just 4-9 ATS as a home favorite of -3.5 to -10.5. Make the play on Chicago.

The Steelers have been regressing ever since their huge start a season ago. This may well be Big Ben's swan song as his numbers in terms of yards per attempt have been steadily declining. He also has a very soft offensive line in front of him. He is getting banged up on a weekly basis, and once again has an injury although he will play through it. T.J. Watt left last game and is questionable this week, as the injuries are piling up already. The Steelers had a big win in their opener vs Buffalo, but were out-played and out-gained by over 100 yards. They had a golden opportunity last week vs the Raiders who were off a short week, and traveling across the country. They were physically beaten, and were out-gained by nearly 100 yards. Cincinnati beat Minnesota, and lost to Chicago by just 3 despite imploding offensively with 4 turnovers. They held the Bear's to 206 total yards. The Bengals can only blame themselves for not being 3-0, and right now the optics on Pittsburgh are not good. Make the play on Cincinnati.