Minnesota @ Michigan State 3:30 PM ET

Game# 337-338

Play On: Minnesota -3.0 (5*)

The Gophers enter this matchup with an unblemished 3-0 record after recording 3 home wins. They outgained those 3 opponents by an enormous 384.4 yards per game and displayed a dominating running game while doing so. Since the start of last season, Minnesota is 6-0 SU&ATS when coming off a home win and won by 30.2 points per game. Minnesota has gone 3-0 SU&ATS as a conference home favorite of 8.0 or less under current head coach P.J. Fleck and won by a decisive margin of 25.0 points per game. Conversely, Michigan State is coming off a humbling 39-28 loss at Washington in a game they also the Huskies to rack up 503 yards of total offense.

Any college football away team with a point-spread of +1.5 to -4.5 playing in a Game 4, and is 3-0 to start the season, and they allowed 23 points or fewer in their previous games which came versus a non-conference opponent, resulted in those away teams going 11-0 SU&ATS since 1987. The average margin of victory was by 12.0 points per game. Give me Minnesota minus the points.

Duke @ Kansas 12:00 PM ET

Game# 361-362

Play On: Duke +7.5 (5*)

Someone is going to come out of this game with a 4-0 record. Raise your hand if you predicted that kind of start from either team. Now your hand down if you raised because you’re either a pathological or blatant liar. Kansas is coming off upset wins as an away underdog at Houston and West Virginia. Despite their 3-0 start with 1 of those wins coming on the road, Duke is just 10-18 in their last 28 away games. The Blue Devils are at a +5 turnover differential thus far in 2022.

Since 1980, any non-conference college football away underdog of 2.5 to 9.5 that’s coming off 2 or more wins in a row, and they’ve won 11 or fewer of its last 28 road games, versus an opponent off 2 straight away underdog SU upset win, resulted in those away underdogs going 8-0 ATS. Those away underdogs also won 6 of those 8 contests straight up. Give me Duke plus the points.

Baylor @ Iowa State 12:00 PM ET

Game# 313-314

Play On: Iowa State -133 (5*)

Iowa State is coming off a 43-10 shellacking of Ohio U. and outgained them by an enormous by 230 yards. The Cyclones are allowing a mere 234.3 yards per game which has sparked them to a 3-0 start to the season. The Cyclones defense has yet to allow an opponent to rush for 100 or more yards. Since 2020, Iowa State has gone 6-0 SU&ATS at home after allowing 125 yards or less rushing in each of their previous 2 games. Additionally, Iowa State will be playing with revenge by way of last year’s 31-29 loss at Baylor in a game that the Cyclones closed as a 7.0-point road favorite.

Any college football home team that allows 285 yards or fewer per contest and is coming off a game in which they outgained their opponent by 225 yards or more, resulted in those home teams going 34-2 SU (94.4%) since 2018. Give me Iowa State on the money line.

Clemson @ Wake Forest 12:00 PM ET

Game# 339-340

Play On: Wake Forest +7.0 (5*)

Talk about revenge, Wake Forest has lost their last 13 games versus Clemson and 12 of those defeats came by 10 points or more. However, most of those matchups involved Wake Forest teams not as good as this current edition and Clemson teams much better than this one in 2022. The Demon Deacons have established a strong home field in recent years. They’ve won 11 straight at home and are 17-2 in their last 19 in Winston-Salem, North Carolina. That certainly bodes well when considering they’re a home underdog on Saturday. The Demon Deacons were caught looking ahead in last week’s 37-36 home win over Liberty in a game they closed as a 17.0-point favorite. Give me Wake Forest plus the points.